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A Polycomb Repression Signature in Metastatic Prostate Cancer Predicts Cancer Outcome -- Yu et al. 67 (22): 10657 -- Cancer Research

Citation added: November 28th, 2007, 5:03 pm
The Polycomb Group (PcG) protein EZH2 is a critical component of a multiprotein complex that methylates Lys27 of histone 3 (H3K27), which consequently leads to the repression of target gene expression. We have previously reported that EZH2 is overexpresse
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microarray | predictor | cancer | chinnaiyan

Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer : Abstract : Nature

Citation added: August 1st, 2007, 11:10 am
Because the common factor of these rearrangements is aberrant ETV1 overexpression, we recapitulated this event in vitro and in vivo, demonstrating that ETV1 overexpression in benign prostate cells and in the mouse prostate confers neoplastic phenotypes.
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chinnaiyan | microarray | predictor | cancer | j.nature

Taking gene-expression profiling to the clinic: when will molecular signatures become relevant to patient care? : Article : Nature Reviews Cancer

Citation added: June 22nd, 2007, 1:51 pm
The advent of microarray technology has enabled scientists to simultaneously investigate the expression of thousands of genes. Gene-expression profiling studies have provided a molecular classification of breast cancer into clinically relevant subtypes, n
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j.natrevcancer | microarray | cancer | predictor | review | **

Prediction of central nervous system embryonal tumour outcome based on gene expression : Article : Nature

Citation added: March 13th, 2007, 7:27 am
Here we demonstrate that medulloblastomas are molecularly distinct from other brain tumours including primitive neuroectodermal tumours (PNETs), atypical teratoid/rhabdoid tumours (AT/RTs) and malignant gliomas. Previously unrecognized evidence supporting
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j.nature | golub | pomeroy | predictor | microarray | cancer | mq

A Five-Gene Signature and Clinical Outcome in Non-Small-Cell Lung Cancer

Citation added: January 4th, 2007, 7:34 am
"Our five-gene signature is closely associated with relapse-free and overall survival among patients with NSCLC."
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predictor | microarray | cancer | lung.cancer | j.nejm | references

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The "Cancer Citations" area of Footnotez is authored by 5 unique contributors. "Cancer Citations" is also available as a RSS feed for syndication.

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