Cancer Citations > 'Dichloroacetate'

'Dichloroacetate' Oriented Websites

Official University of Alberta DCA (dichloroacetate) site

Citation added: March 25th, 2007, 5:20 pm
Official researchers' information about dichloroacetate chemotherapy for cancer.
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health-care | cancer | dichloroacetate

PCT patent application (WO/2006/108276) A Method of Treating Cancer Using Dichloroacetate, PCT/CA2006/000548, filed by Evangelos Michelakis and Stephen Archer, 2006-04-11.

Citation added: February 23rd, 2007, 6:55 am
References "60/669,884 11.04.2005 US" for "priority data". "The invention relates to the use of dichloroacetate and chemical equivalents thereof for the treatment of cancer by inducing apoptosis or reversing apoptosis-resistance in a cell. Preferably, the
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dichloroacetate | health-care | cancer | medicine | patents

Researchers launch website on new cancer research, from Evangelos Michelakis and Stephen Archer, via CTV.ca

Citation added: February 23rd, 2007, 6:55 am
800 words on the most pressing questions about dichloroacetate: efficacy and safety are not certain until after clinical trials, and although there's a use patent filed, the researchers haven't been able to find investors.
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dichloroacetate | health-care | cancer | medicine

"A Mitochondria-K+ Channel Axis Is Suppressed in Cancer and Its Normalization Promotes Apoptosis and Inhibits Cancer Growth", from Sébastien Bonnet, et al., and Evangelos D. Michelakis

Citation added: February 23rd, 2007, 6:55 am
The dichloroacetate-as-a-cure-for-cancer article; PDF available for US$30. "The unique metabolic profile of cancer (aerobic glycolysis) might confer apoptosis resistance and be therapeutically targeted. Compared to normal cells, several human cancers hav
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dichloroacetate | health-care | research | cancer | medicine

In which my words will be misinterpreted as "proof" that I am a "pharma shill", from pseudonymous cancer surgeon "Orac", 2007-01-22

Citation added: February 23rd, 2007, 6:54 am
3100 words of the best review I've seen on dichloroacetate, pointing out that it's less effective in animal models than angiostatin was, and that the Warburg Effect it targets is only shared by 60-90% of human cancers.
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dichloroacetate | health-care | cancer | medicine

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