Cancer Citations > 'Chinnaiyan'

'Chinnaiyan' Oriented Websites

A Polycomb Repression Signature in Metastatic Prostate Cancer Predicts Cancer Outcome -- Yu et al. 67 (22): 10657 -- Cancer Research

Citation added: November 28th, 2007, 5:03 pm
The Polycomb Group (PcG) protein EZH2 is a critical component of a multiprotein complex that methylates Lys27 of histone 3 (H3K27), which consequently leads to the repression of target gene expression. We have previously reported that EZH2 is overexpresse
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Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer : Abstract : Nature

Citation added: August 1st, 2007, 11:10 am
Because the common factor of these rearrangements is aberrant ETV1 overexpression, we recapitulated this event in vitro and in vivo, demonstrating that ETV1 overexpression in benign prostate cells and in the mouse prostate confers neoplastic phenotypes.
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